Monthly malaria chemoprevention shows potential in an area of very high, perennial malaria transmission
نویسندگان
چکیده
Context New approaches are needed for malaria control where the burden has remained high despite scaled up coverage of long-lasting insecticide-treated nets (LLIN) and prompt access to artemisinin-based combination therapies (ACTs). Bigira and colleagues evaluated three regimens for chemoprevention of malaria in young children in eastern Uganda, in an area of very high yearround malaria transmission and high resistance to antifolate drugs, including sulfadoxine-pyrimethamine (SP) and sulfamethoxazole.
منابع مشابه
Protective Efficacy and Safety of Three Antimalarial Regimens for the Prevention of Malaria in Young Ugandan Children: A Randomized Controlled Trial
BACKGROUND Chemoprevention offers a promising strategy for prevention of malaria in African children. However, the optimal chemoprevention drug and dosing strategy is unclear in areas of year-round transmission and resistance to many antimalarial drugs. To compare three available regimens, we conducted an open-label randomized controlled trial of chemoprevention in Ugandan children. METHODS A...
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